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More information about licensed prescription medicines
Mounjaro
Mounjaro
Mounjaro
Mounjaro is a prescription medicine used to support weight management. It is also licensed for type
2 diabetes. It works best when combined with healthy eating, increased activity, and regular
medical follow-up.
■ How Does it Work?
Mounjaro works by mimicking two natural hormones in the body, GLP-1 and GIP. Together they
help to:
• Reduce appet
Mounjaro is a prescription medicine used to support weight management. It is also licensed for type
2 diabetes. It works best when combined with healthy eating, increased activity, and regular
medical follow-up.
■ How Does it Work?
Mounjaro works by mimicking two natural hormones in the body, GLP-1 and GIP. Together they
help to:
• Reduce appetite – you feel full sooner and stay full longer
• Slow down stomach emptying – food stays in your stomach longer
• Improve blood sugar control – especially helpful if you have diabetes or are at risk
■ How Do I Take It?
Mounjaro comes as a once-weekly injection using a pen device. It is injected under the skin
(tummy, thigh, or upper arm). You can take it at any time of day, with or without food.
Week Dose
1–4 2.5 mg once weekly (starting dose)
5–8 5 mg once weekly
9–12 7.5 mg once weekly
13–16 10 mg once weekly
17–20 12.5 mg once weekly
21+ 15 mg once weekly (maximum dose)
■ Tips for Taking Mounjaro
• Inject once a week, on the same day each week
• Rotate injection sites each week
• If you miss a dose, take it within 4 days; if more than 4 days have passed, skip it and continue
as normal
• Store unused pens in the fridge; once in use, pens can be kept at room temperature (up to
30°C) for 21 days
■ Common Side Effects
• Nausea, vomiting, diarrhoea, or constipation
• Reduced appetite
• Tiredness or headache
• Mild redness or swelling at the injection site
Contact your doctor if symptoms are severe, persistent, or if you notice abdominal pain that does
not go away.
■ Monitoring
Your doctor will review your weight, progress, and any side effects regularly. Treatment may be
adjusted depending on how you respond. Progress is usually checked after 16 weeks on the 5 mg
dose or higher.
https://www.medicines.org.uk/emc/files/pil.15481.pdf
Wegovy
Mounjaro
Mounjaro
Wegovy is a prescription medicine used for weight management. It works best when combined with
healthy eating, increased activity, and regular medical follow-up.
■ How Does it Work?
Wegovy mimics a natural hormone in the body called GLP-1. It works in several ways to support
weight loss:
• Reduces appetite – helping you feel full sooner and st
Wegovy is a prescription medicine used for weight management. It works best when combined with
healthy eating, increased activity, and regular medical follow-up.
■ How Does it Work?
Wegovy mimics a natural hormone in the body called GLP-1. It works in several ways to support
weight loss:
• Reduces appetite – helping you feel full sooner and stay full longer
• Slows down stomach emptying – food stays in your stomach longer
• Supports blood sugar control – reducing cravings and stabilising energy levels
■ How Do I Take It?
Wegovy is taken once a week as an injection under the skin (in your tummy, thigh, or upper arm).
You can take it at any time of day, with or without food.
Weeks Dose
1–4 0.25 mg once weekly
5–8 0.5 mg once weekly
9–12 1.0 mg once weekly
13–16 1.7 mg once weekly
17+ 2.4 mg once weekly (maintenance dose)
■ Tips for Taking Wegovy
• Inject once a week, on the same day each week
• Rotate injection sites each week
• If you miss a dose and it is within 5 days, take it as soon as possible. If more than 5 days
have passed, skip it and continue as normal
• Store unused pens in the fridge; once in use, pens can be kept at room temperature (up to
30°C) for 6 weeks
■ Common Side Effects
• Nausea, vomiting, diarrhoea, or constipation
• Headache or tiredness
• Mild redness or swelling at the injection site
Contact your doctor if symptoms are severe, persistent, or if you notice abdominal pain that does
not go away.
■ Monitoring
Your doctor will review your weight, progress, and any side effects regularly. Treatment is usually
reassessed after 16 weeks on the 2.4 mg dose to check effectiveness.
Saxenda
Mounjaro
Saxenda
Saxenda is a prescription medicine used to support weight management. It works best when
combined with healthy eating, increased activity, and regular medical follow-up.
■ How Does it Work?
Saxenda is similar to a natural hormone in the body called GLP-1. It helps to:
• Reduce appetite – you feel full sooner and stay full longer
• Slow down st
Saxenda is a prescription medicine used to support weight management. It works best when
combined with healthy eating, increased activity, and regular medical follow-up.
■ How Does it Work?
Saxenda is similar to a natural hormone in the body called GLP-1. It helps to:
• Reduce appetite – you feel full sooner and stay full longer
• Slow down stomach emptying – food stays in your stomach longer
• Support blood sugar control – helpful if you are at risk of diabetes
■ How Do I Take It?
Saxenda comes as a daily injection using a pen device. It is injected under the skin (tummy, thigh,
or upper arm).
Week Dose
1 0.6 mg once daily
2 1.2 mg once daily
3 1.8 mg once daily
4 2.4 mg once daily
5+ 3.0 mg once daily (usual full dose)
■ Tips for Taking Saxenda
• Take it at the same time each day, with or without food
• Rotate injection sites each day
• Store unused pens in the fridge; once in use, can be kept at room temperature for 30 days
• Never share your pen with anyone else
■ Common Side Effects
• Nausea, vomiting, diarrhoea, or constipation
• Headache or tiredness
• Mild redness or swelling at the injection site
Contact your doctor if symptoms are severe, persistent, or if you notice abdominal pain that does
not go away.
■ Monitoring
You will have regular follow-up with your doctor to review your progress, weight loss, and any side
effects. Treatment is usually reassessed after 16 weeks to check effectiveness.
Oral medications
Mysimba
Mysimba is a prescription-only oral medication used alongside a reduced-calorie diet and increased
physical activity. It is licensed for adults with BMI ≥30, or BMI ≥27 with a weight-related condition
such as type 2 diabetes, high blood pressure, or dyslipidaemia.
■ How Does it Work?
Mysimba combines two medicines – naltrexone and bupropion – that act on the brain to:
• Reduce appetite and cravings
• Help you feel full with less food
■ How Do I Take It?
Mysimba is taken as tablets by mouth. The dose is increased gradually over 4 weeks.
Week Dose
1 1 tablet in the morning
2 1 in the morning + 1 in the evening
3 2 in the morning + 1 in the evening
4+ 2 in the morning + 2 in the evening (maximum dose)
■ Effectiveness & Review
Treatment should be stopped after 16 weeks if you have not lost at least 5% of your starting weight.
Studies show average weight loss of around 8% after 56 weeks with Mysimba.
■ Common Side Effects
• Nausea, vomiting, constipation
• Headache, dizziness, dry mouth
• Insomnia (trouble sleeping)
■■ Mysimba may cause drowsiness or dizziness. Do not drive or operate machinery until you know
how it affects you.
■ Monitoring
Regular follow-up with your doctor is important to review progress, side effects, and whether
treatment should continue.
Orlistat
Orlistat is a medicine used to help with weight loss. It works best when combined with a
reduced-calorie diet and regular physical activity. It is suitable for adults with a BMI ≥30, or BMI ≥28
with a weight-related health condition.
■ How Does it Work?
Orlistat works in your digestive system by blocking the absorption of around one-third of the fat from
the food you eat. This undigested fat passes through the gut and out of the body in your stool. By
reducing the calories you absorb from fat, Orlistat helps with weight loss.
■ How Do I Take It?
• The usual dose is 120 mg three times a day.
• Take immediately before, during, or up to 1 hour after a main meal containing fat.
• If a meal is missed or contains no fat, skip the dose.
• Swallow the capsule whole with water.
■ Tips for Taking Orlistat
• Follow a balanced, reduced-calorie diet with about 30% of calories from fat.
• Spread your daily fat intake evenly across three meals.
• Take a daily multivitamin at bedtime (or at least 2 hours after taking Orlistat) to prevent
vitamin deficiencies (A, D, E, K).
■ Common Side Effects
• Oily or fatty stools
• Urgent or increased bowel movements
• Flatulence with oily spotting
• Abdominal discomfort
These side effects are more likely if you eat a high-fat meal.
■ Monitoring
Your doctor will review your progress after 12 weeks. If you have not lost at least 5% of your
starting weight, treatment may be stopped. Regular follow-up ensures safe and effective use.
Practical tips
The most common side effects observed in clinical trials were nausea and diarrhoea, these were mild/moderate in severity, and usually of short duration and most frequently reported during the first few months on treatment.
- Try: Eating smaller portions
- Try: Eating slowly
- Try: to stay hydrated
- Try: To stop eating at first sign of fullness
- Avoid: Large portions
- Avoid: Fried or fatty foods
- Avoid: Overly sweet or spicy foods
- Avoid: Drinking alcohol and smoking cigarettes
Read the patient leaflet and information you have been provided and contact us on the number you have been given or via the contact us page.